Clinical Immunology, Global Infections, and Therapeutics

This module begins with discussion of immune cells, molecules and mediators to develop your understanding and knowledge of advanced immunological concepts. The module will focus on how immune system disorders arise in allergy, autoimmunity, immunodeficiency and transplantation, and how current and modern techniques investigate and diagnose disease. This module will explore host:pathogen interactions in infections focusing on examples of the most current global infectious diseases in humans (tuberculosis, HIV/AIDS, malaria, COVID-19). You will also learn about current immunological methods such as vaccination, and monoclonal therapeutic antibodies and how they are adapted for use in the clinical setting.

1. Review of the pathophysiology, diagnosis and treatment of hypersensitivity, autoimmunity, immunodeficiency and transplantation

2. Demonstrate critical understanding of immunological testing in disease diagnosis and developing technologies

3. Critically discuss the ways in which microorganism and the host immune response affects the pathology of global infectious diseases and how this relates to clinical symptoms.

4. Read, interpret and critically analyse primary literature on the immunology of disease

5. Evaluate and discuss strategies which modulate the immune system and their therapeutics